HAEMOGLOBINOPATHIES UNIT
The unit was established on the 6th of March, 1996. It is interested in the wide range of inherited blood disorders which are common in Basrah and South of Iraq, it iclude:
Sickle cell disease
thalassemia disorders
red blood cell enzymopathies as glucose 6 phosphate dehydrogenase deficiency
The unit conduct research in all the medical aspects of the above mentioned disorders including clinical, epidemiological, therapeutic and laboratory aspects.
The unit also offer diagnostic laboratory service for patients. The unit is in close collaboration with the thalassemia treatment center in Basrah
Laboratory service:
Laboratory service offered to patients referred to the unit from various hospitals
Hemoglobin electrophoresis
Sickling phenomena
Fetal hemoglobin estimation
Glucose 6-phosphate dehydrogenase enzyme
Hemoglobin variant estimation
Scientific workshops:
The unit hold workshop each year to discuss the research work conducted and the recent advances in the field
The first workshop held 29.11.1996
The second 17.4.1997
The third 15.9.1999
The fourth 15.11.2001
The fifth 23.12.2002
The sixth 18.5.2006
The seventh will be 15.2.2008
Staff:
Affiliate to the unit a wide range of medical, scientific and research staff in tall the major clinical specialties
Future direction:
The unit is interested in expanding its works in the following fields:
The establishment of genetic counseling clinic for premarital examination and
Advice
The exploration of genetic basis of Thalassemia defect in our population by DNA studies.
Research:
The unit published more than 50 research titles in various aspects of hemoglibinopathies
Selected Published research work
1. M.K.Hassan, J.Y.Taha, L.M. Al-Naama, N.M.Widad and S.N.Jasim . Frequency of haemoglobinopathies and glucose-6-phosphate dehydrogenase deficiency in Basrah. Eastern Mediterranean Health Journal, 2003; Vol.9., No.1 &2
2. L.M.Al-Naama, I.A.Al-Sadoon and M.M.Al-Naama. Neonatal Jaundice and glucose-6-
phosphate dehydrogenase deficiency in Basrah. Annals of tropical Paediatrics, 1987;7: 134-138
3. M.M.Al-Naama, L.M.Al-Naama and T.A.Al-Sadoon . Glucose-6-Phosphate dehydrogenase and pyruvate kinase activities in erythrocytes of neonates and adults in Basrah. Annals of Tropical Paediatrics. 1994; 14,195-200
4. N.M.Widad, L.M.Al-Naama and M.K.Hassan( 2003) Trace element in patients with ß-thalassemia major. Haematology, 2003; 6: 376-383
5. N. M. Widad, L. M. Al-Naama, M. K. Hassan . Lipid peroxidation in beta-thalassaemia . Haema 2006; 9
6. N. M.Widad, L. M. Al-Naama, M. K. Hassan . Iron status in subjects with ‚-thalassaemia minor . Haematology 2004; 7: 321-325
7. M. K. Hassan L. M. Al-Naama. Glucose tolerance in thalassemia.Baaabylon Medical Journal 2004;7:296-300
Research projects for 2009
1. Antioxidant enzymes in Hbs
2. Lipid profile in thalassemic patients
3. Lipid peroxidation in sickle cell disease
4. Pulmonary hypertension in patients with sickle cell disease
5. Pulmonary hypertension in patients with beta-thalassemia
6. Atherogenic risk in patients with beta-thalassemia
7. Health quality of life in patients with B-thalassemia major
8. Health related quality of life in patients with sickle cell anaemia